Posts tagged neuromod

Personalized tACS Pipeline

Working memory difficulties are among the first signs of psychosis, and current medication does little to improve them. Young people with 22q11.2 deletion syndrome are at high risk of psychosis, which makes alternative treatments especially important for them.

Flowchart. EEG recorded during a working memory task is preprocessed in Cartool. T1- and T2-weighted MRI is segmented with FreeSurfer and used to compute an individual inverse model in Cartool. Both feed a toolbox for ROI delimitation, inverse transformation, and singular value decomposition, followed by theta-gamma phase-amplitude coupling in Matlab. In parallel, SimNIBS segments, meshes, and simulates electric current density. The outputs are the stimulation parameters, which theta rhythm and at what intensity.

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